The findings suggest that muscle-like co-ordination may arise not only from biochemical processes but also from the underlying physical architecture of the system. Credit: University of Bristol.
Scientists have developed a network of mechanical motors that mimic the molecular machinery underpinning human muscle contraction.
The University of Bristol-led findings could open new possibilities for artificial muscles in robotics.
In humans, muscles work through the co-ordinated activity of thousands of molecular motors called actomyosin which help make them contract.
Despite this complex biochemical process, they reliably display distinctive collective behaviours.
For example, under increasing load human muscles can recruit more motors, a bit like bringing in more working parts into action when extra strength is needed.
In this study, researchers reveal that networks of simple mechanical motors can replicate the key features of actomyosin, the molecular machinery underpinning muscle contraction.
Rather than modelling these intricate molecular interactions directly, the Bristol team created a simplified system in which motors interact only through brief mechanical contact within a carefully designed geometry.
To test this theory, the researchers built an experimental tabletop model using small electric motors arranged like real muscle proteins, in an actomyosin-like configuration.
The device ‘self-organised’ into co-ordinated travelling waves of motion and automatically adapted as the mechanical load increased, just like human muscles.
The physical demonstration was built using small electric motors combined with custom 3D-printed plastic components and laser-cut acrylic.
Remarkably, this minimal system reproduced the similar collective behaviours observed in the mechanics behind real muscles.
Study team leader, Dr Hermes Bloomfield-Gadêlha, senior lecturer in applied mathematics and data modelling at the University of Bristol, explained: “The motors aren’t ‘talking’ to each other directly. Each one pushes on a shared backbone structure, which changes what the others feel.
“Over time, that feedback causes them to fall into co-ordinated patterns on their own — a bit like rowers synchronising their strokes or the classic synchronisation seen in pendulum clocks.”
The physical demonstration was built using small electric motors combined with custom 3D-printed plastic components and laser-cut acrylic. Credit: University of Bristol.
Physical architecture
The findings suggest that muscle-like co-ordination may arise not only from biochemical processes but also from the underlying physical architecture of the system.
This insight could influence future research in both biology and engineering.
In soft robotics, the principles could help engineers design adaptive artificial muscles that organise themselves naturally rather than relying on complex control systems.
Bloomfield-Gadêlha said: “On the engineering side, we’re interested in whether these ideas could help design artificial muscles or soft robotic systems that adapt automatically.
“While from a biological perspective, it also raises questions about how much of muscle behaviour depends on motor chemistry and how much comes from the organisation of the system.
“Understanding that balance could help us better understand muscle health, disease, ageing and conditions such as muscular dystrophy.”
The study is published in the Journal of the Royal Society Interface.
